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glut1 inhibitor bay 876  (MedChemExpress)


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    MedChemExpress glut1 inhibitor bay 876
    F-actin and nuclei in HuCCT1 and RBE cells transfected with si-NC, si-CD109 or si-EFNB2 and treated with 5 <t>µM</t> <t>BAY-876</t> or 1 µM TCEP for 24 h. si, small interfering; NC, negative control; TCEP, Tris-(2-carboxyethyl)-phosphine hydrochloride.
    Glut1 Inhibitor Bay 876, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 63 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/glut1 inhibitor bay 876/product/MedChemExpress
    Average 95 stars, based on 63 article reviews
    glut1 inhibitor bay 876 - by Bioz Stars, 2026-02
    95/100 stars

    Images

    1) Product Images from "Exploring the role of disulfidptosis-related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma"

    Article Title: Exploring the role of disulfidptosis-related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

    Journal: Oncology Reports

    doi: 10.3892/or.2026.9042

    F-actin and nuclei in HuCCT1 and RBE cells transfected with si-NC, si-CD109 or si-EFNB2 and treated with 5 µM BAY-876 or 1 µM TCEP for 24 h. si, small interfering; NC, negative control; TCEP, Tris-(2-carboxyethyl)-phosphine hydrochloride.
    Figure Legend Snippet: F-actin and nuclei in HuCCT1 and RBE cells transfected with si-NC, si-CD109 or si-EFNB2 and treated with 5 µM BAY-876 or 1 µM TCEP for 24 h. si, small interfering; NC, negative control; TCEP, Tris-(2-carboxyethyl)-phosphine hydrochloride.

    Techniques Used: Transfection, Negative Control



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    glut1 inhibitor bay 876  (MedChemExpress)
    95
    MedChemExpress glut1 inhibitor bay 876
    F-actin and nuclei in HuCCT1 and RBE cells transfected with si-NC, si-CD109 or si-EFNB2 and treated with 5 <t>µM</t> <t>BAY-876</t> or 1 µM TCEP for 24 h. si, small interfering; NC, negative control; TCEP, Tris-(2-carboxyethyl)-phosphine hydrochloride.
    Glut1 Inhibitor Bay 876, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/glut1 inhibitor bay 876/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    glut1 inhibitor bay 876 - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    glut1 inhibitor  (MedChemExpress)
    95
    MedChemExpress glut1 inhibitor
    F-actin and nuclei in HuCCT1 and RBE cells transfected with si-NC, si-CD109 or si-EFNB2 and treated with 5 <t>µM</t> <t>BAY-876</t> or 1 µM TCEP for 24 h. si, small interfering; NC, negative control; TCEP, Tris-(2-carboxyethyl)-phosphine hydrochloride.
    Glut1 Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/glut1 inhibitor/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    glut1 inhibitor - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    glut1 inhibitor bay876  (MedChemExpress)
    95
    MedChemExpress glut1 inhibitor bay876
    F-actin and nuclei in HuCCT1 and RBE cells transfected with si-NC, si-CD109 or si-EFNB2 and treated with 5 <t>µM</t> <t>BAY-876</t> or 1 µM TCEP for 24 h. si, small interfering; NC, negative control; TCEP, Tris-(2-carboxyethyl)-phosphine hydrochloride.
    Glut1 Inhibitor Bay876, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/glut1 inhibitor bay876/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    glut1 inhibitor bay876 - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    glut1 inhibitor bay 876  (Selleck Chemicals)
    93
    Selleck Chemicals glut1 inhibitor bay 876
    Figure 4. <t>GLUT1</t> is a target of miR-22 in HCC and regulates cell metabolism. (A) WB analysis of GLUT1 expression in the miR-22-silenced (MZIP-22) HepG2 cells and miR-22-overexpressing (pMXs-22) Huh-7 cells and related controls (shRNA). GAPDH was used as a housekeeping gene; WB analysis was performed in two independent experiments. GLUT1 molecular weight (MW) is from 45 to 60 kDa, and all the bands in this MW range have been considered for the analysis. (B) Dual-luciferase activity assay of wild-type (WT) and mutant (MUT) GLUT1-3′UTR vectors co-transfected with miR-22 in HepG2 and Huh-7 cells. NC: negative control precursor miRNA.
    Glut1 Inhibitor Bay 876, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/glut1 inhibitor bay 876/product/Selleck Chemicals
    Average 93 stars, based on 1 article reviews
    glut1 inhibitor bay 876 - by Bioz Stars, 2026-02
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    F-actin and nuclei in HuCCT1 and RBE cells transfected with si-NC, si-CD109 or si-EFNB2 and treated with 5 µM BAY-876 or 1 µM TCEP for 24 h. si, small interfering; NC, negative control; TCEP, Tris-(2-carboxyethyl)-phosphine hydrochloride.

    Journal: Oncology Reports

    Article Title: Exploring the role of disulfidptosis-related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

    doi: 10.3892/or.2026.9042

    Figure Lengend Snippet: F-actin and nuclei in HuCCT1 and RBE cells transfected with si-NC, si-CD109 or si-EFNB2 and treated with 5 µM BAY-876 or 1 µM TCEP for 24 h. si, small interfering; NC, negative control; TCEP, Tris-(2-carboxyethyl)-phosphine hydrochloride.

    Article Snippet: Cells were then treated with the GLUT1 inhibitor BAY-876 (10 μM; cat. no. HY-100017, MedChemExpress) and/or the reducing agent, Tris-(2-carboxyethyl)-phosphine hydrochloride (TCEP; 20 mM; cat. no. A600974; Sangon Biotech Co., Ltd.) for 6 h at 37°C.

    Techniques: Transfection, Negative Control

    Figure 4. GLUT1 is a target of miR-22 in HCC and regulates cell metabolism. (A) WB analysis of GLUT1 expression in the miR-22-silenced (MZIP-22) HepG2 cells and miR-22-overexpressing (pMXs-22) Huh-7 cells and related controls (shRNA). GAPDH was used as a housekeeping gene; WB analysis was performed in two independent experiments. GLUT1 molecular weight (MW) is from 45 to 60 kDa, and all the bands in this MW range have been considered for the analysis. (B) Dual-luciferase activity assay of wild-type (WT) and mutant (MUT) GLUT1-3′UTR vectors co-transfected with miR-22 in HepG2 and Huh-7 cells. NC: negative control precursor miRNA.

    Journal: International journal of molecular sciences

    Article Title: MiR-22/GLUT1 Axis Induces Metabolic Reprogramming and Sorafenib Resistance in Hepatocellular Carcinoma.

    doi: 10.3390/ijms26083808

    Figure Lengend Snippet: Figure 4. GLUT1 is a target of miR-22 in HCC and regulates cell metabolism. (A) WB analysis of GLUT1 expression in the miR-22-silenced (MZIP-22) HepG2 cells and miR-22-overexpressing (pMXs-22) Huh-7 cells and related controls (shRNA). GAPDH was used as a housekeeping gene; WB analysis was performed in two independent experiments. GLUT1 molecular weight (MW) is from 45 to 60 kDa, and all the bands in this MW range have been considered for the analysis. (B) Dual-luciferase activity assay of wild-type (WT) and mutant (MUT) GLUT1-3′UTR vectors co-transfected with miR-22 in HepG2 and Huh-7 cells. NC: negative control precursor miRNA.

    Article Snippet: The cells were treated with 2.5–5.0 μM sorafenib tosylate (Bayer, Leverkusen, Germany) or 2.5–5.0 μM GLUT1 inhibitor BAY-876 or 100 μM CoCl2 (Selleck Chemicals, Houston, TX, USA).

    Techniques: Expressing, shRNA, Molecular Weight, Luciferase, Activity Assay, Mutagenesis, Transfection, Negative Control

    Figure 5. miR-22 downregulation is associated with sorafenib resistance in HCC. (A) Growth curves of the miR-22-silenced (MZIP-22) HepG2 cells and miR-22-overexpressing (pMXs-22) Huh-7 cells and re- lated controls (shRNA) under sorafenib treatment. Rescue experiment in the miR-22-silenced (MZIP-22) HepG2 cells treated with the GLUT1-inhibitor BAY-876 or vehicle (DMSO) and sorafenib. The growth curves were normalized to T0. Mean ± SD values are reported. Two independent experiments were performed in quadruplicate. WB analysis of GLUT1 expression in the same setting. WB was performed in two independent experiments, and GAPDH was used as a housekeeping gene. (B,C) Box plot graph of the miR-22 (B) and GLUT1 (C) levels in responder (N = 8) and non-responder (N = 7) HCC nodules from sorafenib-treated rats. The Y-axis reports the 2−∆∆Ct values corresponding to the miR-22 or GLUT1 levels. Correlation graph between miR-22 (B) or GLUT1 (C) expression and tumor volume of sorafenib-treated DEN-HCC rats. The axes report the 2−∆∆Ct values corresponding to mRNA levels and tumor size (mm3) of HCC nodules transformed in a log2 form. Beta-actin or U6RNA were used as housekeeping genes. Real-Time PCR analysis was run in triplicate. (D) Correlation graphs between the

    Journal: International journal of molecular sciences

    Article Title: MiR-22/GLUT1 Axis Induces Metabolic Reprogramming and Sorafenib Resistance in Hepatocellular Carcinoma.

    doi: 10.3390/ijms26083808

    Figure Lengend Snippet: Figure 5. miR-22 downregulation is associated with sorafenib resistance in HCC. (A) Growth curves of the miR-22-silenced (MZIP-22) HepG2 cells and miR-22-overexpressing (pMXs-22) Huh-7 cells and re- lated controls (shRNA) under sorafenib treatment. Rescue experiment in the miR-22-silenced (MZIP-22) HepG2 cells treated with the GLUT1-inhibitor BAY-876 or vehicle (DMSO) and sorafenib. The growth curves were normalized to T0. Mean ± SD values are reported. Two independent experiments were performed in quadruplicate. WB analysis of GLUT1 expression in the same setting. WB was performed in two independent experiments, and GAPDH was used as a housekeeping gene. (B,C) Box plot graph of the miR-22 (B) and GLUT1 (C) levels in responder (N = 8) and non-responder (N = 7) HCC nodules from sorafenib-treated rats. The Y-axis reports the 2−∆∆Ct values corresponding to the miR-22 or GLUT1 levels. Correlation graph between miR-22 (B) or GLUT1 (C) expression and tumor volume of sorafenib-treated DEN-HCC rats. The axes report the 2−∆∆Ct values corresponding to mRNA levels and tumor size (mm3) of HCC nodules transformed in a log2 form. Beta-actin or U6RNA were used as housekeeping genes. Real-Time PCR analysis was run in triplicate. (D) Correlation graphs between the

    Article Snippet: The cells were treated with 2.5–5.0 μM sorafenib tosylate (Bayer, Leverkusen, Germany) or 2.5–5.0 μM GLUT1 inhibitor BAY-876 or 100 μM CoCl2 (Selleck Chemicals, Houston, TX, USA).

    Techniques: shRNA, Expressing, Transformation Assay, Real-time Polymerase Chain Reaction

    Figure 6. miR-22 circulating levels predict sorafenib resistance in human and rat HCCs. (A) Box plot graph of GLUT1 expression in early HCCs from the Bologna cohort divided based on serum miR-22 levels (high, N = 11; low, N = 10). The Y-axis reports the 2−∆∆Ct values. Mean ± SD values are displayed. GAPDH was used as a housekeeping gene. (B) Correlation graph between the tissue and serum miR-22 expression levels in early HCCs from the Bologna cohort. The axes report the 2−∆∆Ct values corresponding to the

    Journal: International journal of molecular sciences

    Article Title: MiR-22/GLUT1 Axis Induces Metabolic Reprogramming and Sorafenib Resistance in Hepatocellular Carcinoma.

    doi: 10.3390/ijms26083808

    Figure Lengend Snippet: Figure 6. miR-22 circulating levels predict sorafenib resistance in human and rat HCCs. (A) Box plot graph of GLUT1 expression in early HCCs from the Bologna cohort divided based on serum miR-22 levels (high, N = 11; low, N = 10). The Y-axis reports the 2−∆∆Ct values. Mean ± SD values are displayed. GAPDH was used as a housekeeping gene. (B) Correlation graph between the tissue and serum miR-22 expression levels in early HCCs from the Bologna cohort. The axes report the 2−∆∆Ct values corresponding to the

    Article Snippet: The cells were treated with 2.5–5.0 μM sorafenib tosylate (Bayer, Leverkusen, Germany) or 2.5–5.0 μM GLUT1 inhibitor BAY-876 or 100 μM CoCl2 (Selleck Chemicals, Houston, TX, USA).

    Techniques: Expressing